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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CCNE1
All Species:
14.24
Human Site:
S59
Identified Species:
24.1
UniProt:
P24864
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P24864
NP_001229.1
410
47077
S59
T
A
R
D
Q
C
G
S
Q
P
W
D
N
N
A
Chimpanzee
Pan troglodytes
XP_512559
393
44800
P53
N
N
A
V
C
A
D
P
C
S
L
I
P
T
P
Rhesus Macaque
Macaca mulatta
XP_001084995
410
47103
S59
T
A
R
D
Q
C
G
S
Q
P
W
D
N
N
T
Dog
Lupus familis
XP_541724
456
51105
G105
T
A
R
G
Q
C
G
G
Q
P
W
D
N
N
P
Cat
Felis silvestris
Mouse
Mus musculus
Q61457
408
46968
S56
T
V
K
S
E
D
S
S
Q
P
W
D
D
N
S
Rat
Rattus norvegicus
P39949
411
47463
S59
T
V
K
S
Q
D
S
S
Q
P
W
D
D
D
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507249
405
46635
S57
R
H
Q
Y
E
I
R
S
C
W
P
S
M
L
T
Chicken
Gallus gallus
P49707
407
46720
E56
M
S
R
K
K
Q
Y
E
N
Q
L
S
W
N
N
Frog
Xenopus laevis
Q91780
408
47153
G58
K
K
Q
Y
Q
D
R
G
P
W
S
N
E
M
T
Zebra Danio
Brachydanio rerio
P47794
410
46612
P61
A
S
Q
A
C
W
N
P
D
T
G
Y
T
S
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P54733
709
77202
Q274
A
S
S
G
C
S
Q
Q
Q
A
V
N
G
E
R
Honey Bee
Apis mellifera
XP_394802
457
51232
T61
S
Y
T
E
S
C
H
T
V
H
P
L
E
N
S
Nematode Worm
Caenorhab. elegans
O01501
524
60567
H149
L
A
E
S
E
E
S
H
E
M
V
R
L
E
E
Sea Urchin
Strong. purpuratus
XP_785047
424
48468
S70
W
V
P
I
S
E
S
S
S
I
E
T
S
L
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.3
98.2
73.9
N.A.
78.7
79.5
N.A.
49
71.9
60.2
58.2
N.A.
28.2
38.2
24.2
44.5
Protein Similarity:
100
95.3
98.5
81.1
N.A.
88.7
90
N.A.
66.5
85.1
76.8
73.9
N.A.
39.6
55.1
41.4
60.8
P-Site Identity:
100
0
93.3
80
N.A.
46.6
46.6
N.A.
6.6
13.3
6.6
0
N.A.
6.6
13.3
6.6
6.6
P-Site Similarity:
100
0
93.3
80
N.A.
73.3
73.3
N.A.
20
26.6
20
20
N.A.
20
40
20
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
29
8
8
0
8
0
0
0
8
0
0
0
0
8
% A
% Cys:
0
0
0
0
22
29
0
0
15
0
0
0
0
0
0
% C
% Asp:
0
0
0
15
0
22
8
0
8
0
0
36
15
8
0
% D
% Glu:
0
0
8
8
22
15
0
8
8
0
8
0
15
15
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
15
0
0
22
15
0
0
8
0
8
0
0
% G
% His:
0
8
0
0
0
0
8
8
0
8
0
0
0
0
0
% H
% Ile:
0
0
0
8
0
8
0
0
0
8
0
8
0
0
0
% I
% Lys:
8
8
15
8
8
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
8
0
0
0
0
0
0
0
0
0
15
8
8
15
8
% L
% Met:
8
0
0
0
0
0
0
0
0
8
0
0
8
8
0
% M
% Asn:
8
8
0
0
0
0
8
0
8
0
0
15
22
43
8
% N
% Pro:
0
0
8
0
0
0
0
15
8
36
15
0
8
0
22
% P
% Gln:
0
0
22
0
36
8
8
8
43
8
0
0
0
0
0
% Q
% Arg:
8
0
29
0
0
0
15
0
0
0
0
8
0
0
8
% R
% Ser:
8
22
8
22
15
8
29
43
8
8
8
15
8
8
22
% S
% Thr:
36
0
8
0
0
0
0
8
0
8
0
8
8
8
22
% T
% Val:
0
22
0
8
0
0
0
0
8
0
15
0
0
0
0
% V
% Trp:
8
0
0
0
0
8
0
0
0
15
36
0
8
0
0
% W
% Tyr:
0
8
0
15
0
0
8
0
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _